Description

5-Bromo-8-Chloroisoquinoline is a high-purity halogenated isoquinoline derivative, a crucial advanced intermediate in modern synthetic chemistry. Its value lies in its unique bifunctional halogenated structure, which enables precise and efficient derivatization for constructing complex molecular architectures. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and as a key building block for active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A versatile building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a starting material for the creation of organic electronic materials, ligands, and functionalized polymers.
• Chemical Research & Development: Essential for method development, cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), and exploring new synthetic pathways in academic and industrial labs.
• Ligand Synthesis: Used to prepare complex chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: Potential precursor for synthesizing specialized fluorophores and sensing molecules due to the isoquinoline core.

Basic Information

Product Name	5-Bromo-8-Chloroisoquinoline
CAS No.	956003-79-5
Molecular Formula	C9H5BrClN
Molecular Weight	242.50 g/mol
Synonyms	8-Chloro-5-bromoisoquinoline; 5-Bromo-8-chloro-isoquinoline; Isoquinoline, 5-bromo-8-chloro-; 956003-79-5; 5-Br-8-Cl-isoquinoline
EINECS	Contact for details

Quality Control

Our 5-Bromo-8-Chloroisoquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.