Description

tert-Butyl 4-Amino-4,5,6,7-tetrahydro-1H-indazole-1-carboxylate is a high-purity, protected heterocyclic amine building block of significant importance in modern organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require complex heterocyclic cores.
• Chemical Biology & Proteomics: Serves as a building block for designing molecular probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Material Science Research: Employed in the synthesis of specialty polymers, ligands for catalysis, and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic Research: Utilized in university and institutional labs for methodological development in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Item	Details
Product Name	tert-Butyl 4-Amino-4,5,6,7-tetrahydro-1H-indazole-1-carboxylate
CAS No.	955406-82-3
Molecular Formula	C₁₂H₁₉N₃O₂
Molecular Weight	237.30 g/mol
Synonyms	1-Boc-4-amino-4,5,6,7-tetrahydro-1H-indazole; 4-Amino-4,5,6,7-tetrahydro-1H-indazole-1-carboxylic acid tert-butyl ester; tert-Butyl 4-amino-4,5,6,7-tetrahydroindazole-1-carboxylate; 1H-Indazole-1-carboxylic acid, 4-amino-4,5,6,7-tetrahydro-, 1,1-dimethylethyl ester; Boc-4-amino-4,5,6,7-tetrahydroindazole; 4-Amino-1-Boc-4,5,6,7-tetrahydroindazole; 955406-82-3
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Amino-4,5,6,7-tetrahydro-1H-indazole-1-carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and results from techniques such as HPLC, NMR, and MS are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.