Description

2-(1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Propane-1,3-Diol is a specialized organic compound featuring a tetrahydroisoquinoline moiety linked to a propanediol chain, making it a valuable chiral building block and intermediate. This compound matters for its role in the synthesis of complex molecules, particularly in pharmaceutical research where its structure can be leveraged to impart specific biological activity or stereochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the tetrahydroisoquinoline scaffold is beneficial.
• Fine Chemical Production: Serves as a building block for complex ligands, catalysts, and specialty polymers.
• Academic & Industrial Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Process Chemistry: Investigated for scalable routes in the production of bioactive compounds.

Basic Information

Product Name	2-(1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Propane-1,3-Diol
CAS No.	955287-52-2
Molecular Formula	C₁₂H₁₇NO₂
Molecular Weight	207.27 g/mol
Synonyms	1,3-Propanediol, 2-(1,2,3,4-tetrahydro-1-isoquinolinyl)-; 2-(1,2,3,4-Tetrahydroisoquinolin-1-yl)propane-1,3-diol; 1-(1,3-Dihydroxy-2-propyl)-1,2,3,4-tetrahydroisoquinoline; 2-(1,2,3,4-Tetrahydro-1-isoquinolinyl)-1,3-propanediol; THIQ-Propanediol derivative
EINECS	Contact for details

Quality Control

Our 2-(1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Propane-1,3-Diol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.