Description

2-Amino-4-(2-Fluorophenyl)Thiophene-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a distinct thiophene core functionalized with a fluorophenyl group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Kinase Inhibitor Development: A valuable scaffold for creating potent and selective kinase inhibitors, a major class in oncology.
• CNS Drug Discovery: Employed in the research and development of compounds targeting neurological disorders.
• Chemical Biology: Utilized as a probe or tool compound to study biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Item	Details
Product Name	2-Amino-4-(2-Fluorophenyl)Thiophene-3-Carboxamide
CAS No.	954572-89-5
Molecular Formula	C11H9FN2OS
Molecular Weight	236.27 g/mol
Synonyms	2-Amino-4-(2-fluorophenyl)thiophene-3-carboxamide; 4-(2-Fluorophenyl)-2-aminothiophene-3-carboxamide; 2-Fluoro-α-(2-aminothiophene-3-carbonyl)benzene; Thiophene-3-carboxamide, 2-amino-4-(2-fluorophenyl)-; 954572-89-5; 2-Amino-4-(o-fluorophenyl)thiophene-3-carboxylic acid amide
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(2-Fluorophenyl)Thiophene-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be stored away from light. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.