Description

5-Bromo-7-Fluoro-2,3-Dihydro-1H-Indole is a high-value, halogenated indoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both bromine and fluorine substituents on the fused aromatic system, makes it a versatile building block for constructing complex pharmacophores. This compound is primarily sought after by research and development teams within the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry programs targeting CNS disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological and psychiatric conditions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced activity and selectivity.
• Material Science: Serves as a building block for organic electronic materials, such as OLEDs and semiconductors, due to its electron-rich indole core.
• Chemical Biology: Employed as a molecular probe or a tag in the study of biological systems and enzyme mechanisms.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and discovery chemistry projects.
• Custom Synthesis: A starting material for the tailored production of more complex, multi-functionalized indole derivatives for specialized applications.

Basic Information

Product Name	5-Bromo-7-Fluoro-2,3-Dihydro-1H-Indole
CAS No.	954258-03-8
Molecular Formula	C8H7BrFN
Molecular Weight	216.05 g/mol
Synonyms	5-Bromo-7-fluoro-2,3-dihydro-1H-indole; 7-Fluoro-5-bromo-2,3-dihydro-1H-indole; 1H-Indole, 5-bromo-7-fluoro-2,3-dihydro-; 5-Bromo-7-fluoroindoline; 954258-03-8; 5-Br-7-F-2,3-dihydroindole
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-7-Fluoro-2,3-Dihydro-1H-Indole is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our standard quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.