Description

4-Bromo-6,7-Dimethoxy-Isoindolin-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its specific brominated isoindolinone core structure. This compound is critical for the synthesis of complex molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Research: Employed in the synthesis of novel herbicides or fungicides due to its heterocyclic scaffold.
• Chemical Synthesis: Acts as a precursor for more complex isoindolinone derivatives and fused ring systems in organic synthesis.
• Academic Research: Utilized in university and institutional labs for methodological development and studying bromination reactions on heterocycles.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	4-Bromo-6,7-Dimethoxy-Isoindolin-1-One
CAS No.	954239-46-4
Molecular Formula	C10H10BrNO3
Molecular Weight	272.10 g/mol
Synonyms	4-Bromo-6,7-dimethoxy-2,3-dihydro-1H-isoindol-1-one; 6,7-Dimethoxy-4-bromoisoindolin-1-one; 1H-Isoindol-1-one, 4-bromo-6,7-dimethoxy-2,3-dihydro-; 4-Bromo-6,7-dimethoxyisoindolinone; 954239-46-4 (CAS Registry)
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-6,7-Dimethoxy-Isoindolin-1-One is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.