Description

5,6-Dihydro-4H-Cyclopenta[B]Thiophen-4-Ol CAS NO 954238-22-3 is a high-purity, specialized heterocyclic building block featuring a fused cyclopentane-thiophene ring system with a hydroxyl functional group. This compound is valued for its unique molecular architecture, which makes it a critical intermediate in the synthesis of complex organic molecules, particularly in advanced pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its fused ring system for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as novel semiconductors or conductive polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Catalyst Ligand Development: The hydroxyl and sulfur-containing structure can be modified to create novel ligands for asymmetric catalysis.
• Academic & Contract Research: Essential for methodological studies and synthetic chemistry projects in universities and CROs (Contract Research Organizations).

Basic Information

Item	Details
Product Name	5,6-Dihydro-4H-Cyclopenta[B]Thiophen-4-Ol
CAS No.	954238-22-3
Molecular Formula	C7H8OS
Molecular Weight	140.20 g/mol
Synonyms	4-Hydroxy-4,5,6,7-tetrahydrocyclopenta[b]thiophene; 4-Cyclopenta[b]thiophen-4-ol, 5,6-dihydro-; 4H-Cyclopenta[b]thiophen-4-ol, 5,6-dihydro-; Cyclopentathiophen-4-ol; 4-Hydroxy-4,5,6,7-tetrahydrobenzo[b]thiophene (tautomer); Dihydrocyclopentathiophen-4-ol; CPTO (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 5,6-Dihydro-4H-Cyclopenta[B]Thiophen-4-Ol is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our standard grade offers a typical purity of ≥97%, with higher purity grades (≥98%, ≥99%) available for critical applications. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere (e.g., nitrogen or argon) to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.