Description

5-Chloro-6-Fluoro-1H-Indole-2,3-Dione is a high-purity, halogenated isatin derivative, a crucial heterocyclic building block in advanced organic synthesis. Its value lies in its versatile reactivity, serving as a key precursor for synthesizing complex molecules with potential biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used as a building block in the creation of new herbicides, fungicides, and insecticides, leveraging its halogenated indole core.
• Material Science Research: Serves as a precursor for synthesizing specialized organic compounds and functional materials, including dyes and pigments.
• Academic & R&D Laboratories: Employed in methodological studies and as a standard in analytical chemistry for method development and validation.
• Bioconjugation & Probe Development: Its reactive carbonyl groups make it suitable for designing chemical probes and bioconjugates for biochemical assays.

Basic Information

Product Name	5-Chloro-6-Fluoro-1H-Indole-2,3-Dione
CAS No.	953897-06-8
Molecular Formula	C8H3ClFNO2
Molecular Weight	199.57 g/mol
Synonyms	5-Chloro-6-fluoroindoline-2,3-dione; 5-Chloro-6-fluoro-2,3-dihydro-1H-indole-2,3-dione; 5-Chloro-6-fluoroisatin; 6-Fluoro-5-chloroisatin; 5-Chloro-6-fluoro-1H-indole-2,3-dione; 953897-06-8; 5-Cl-6-F-isatin
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-6-Fluoro-1H-Indole-2,3-Dione is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.