Description

5-Chloro-7-Fluoro-2,3-Dihydro-1H-Indole-2,3-Dione is a high-purity, synthetically versatile heterocyclic building block, identified by CAS NO 953894-64-9. This compound is a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its unique halogenated indole-2,3-dione scaffold enables precise molecular modifications. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Development: Serves as a core structure for creating new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Organic Synthesis Building Block: Used in academic and industrial research for constructing complex heterocyclic compounds and functional materials.
• Biochemical Research: Employed as a probe or precursor in studying enzyme inhibition and other biological pathways.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors or photoactive materials due to its conjugated system.

Basic Information

Product Name	5-Chloro-7-Fluoro-2,3-Dihydro-1H-Indole-2,3-Dione
CAS No.	953894-64-9
Molecular Formula	C8H3ClFNO2
Molecular Weight	199.57 g/mol
Synonyms	5-Chloro-7-fluoro-1H-indole-2,3-dione; 5-Chloro-7-fluoro-2,3-dihydroxyindole; 5-Chloro-7-fluoro-2,3-dioxoindoline; 5-Chloro-7-fluoroisatin; 7-Fluoro-5-chloroisatin; 953894-64-9; Isatin, 5-chloro-7-fluoro-
EINECS	Contact for details

Quality Control

Our 5-Chloro-7-Fluoro-2,3-Dihydro-1H-Indole-2,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.