Description

1H-Indole-1-Carboxylic Acid, 4-[[Bis(1-Methylethyl)Amino]Carbonyl]-2-Borono-, 1-(1,1-Dimethylethyl) Ester is a sophisticated boronic acid ester derivative of indole, designed as a key synthetic intermediate for advanced organic transformations. This compound matters for its role in facilitating complex coupling reactions, particularly in the development of novel pharmaceutical candidates and specialty materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate unique indole-based scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester coupling partner for constructing complex biaryl and heterobiaryl structures.
• Agrochemical Research: Used in the development of new active ingredients with specific biological activity.
• Material Science: Employed in the creation of organic electronic materials and functional polymers.
• Chemical Biology & Proteomics: Utilized as a probe or linker in the study of biological systems and protein interactions.
• Academic & Institutional Research: A valuable reagent for methodological development and exploratory synthesis in university and industrial labs.

Basic Information

Item	Details
Product Name	1H-Indole-1-Carboxylic Acid, 4-[[Bis(1-Methylethyl)Amino]Carbonyl]-2-Borono-, 1-(1,1-Dimethylethyl) Ester
CAS No.	953411-04-6
Molecular Formula	C22H31BN2O5
Molecular Weight	414.31 g/mol
Synonyms	4-(Diisopropylcarbamoyl)-2-borono-1H-indole-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(diisopropylcarbamoyl)-2-borono-1H-indole-1-carboxylate; 1-(tert-Butyl) 4-(N,N-diisopropylcarbamoyl)indole-1,2-dicarboxylate 2-boronic acid; Boronic acid, B-[1-[(1,1-dimethylethoxy)carbonyl]-4-[[(1-methylethyl)amino]carbonyl]-1H-indol-2-yl]-; CAS 953411-04-6
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Carboxylic Acid, 4-[[Bis(1-Methylethyl)Amino]Carbonyl]-2-Borono-, 1-(1,1-Dimethylethyl) Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.