Description

n-Methyl-[(5-Piperidinothien-2-Yl)Methyl]Amine is a high-purity, advanced pharmaceutical intermediate featuring a piperidine-substituted thiophene core. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapeutic research. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Ligand Synthesis: Serves as a precursor for the development of selective receptor ligands and enzyme inhibitors.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic & Contract Research: Utilized in university and CRO settings for exploratory research in heterocyclic chemistry and pharmacology.

Basic Information

Product Name	n-Methyl-[(5-Piperidinothien-2-Yl)Methyl]Amine
CAS No.	953409-06-8
Molecular Formula	C11H18N2S
Molecular Weight	210.34 g/mol
Synonyms	1-[5-[(Methylamino)methyl]thiophen-2-yl]piperidine; 2-[(Methylamino)methyl]-5-(1-piperidinyl)thiophene; 5-[(Methylamino)methyl]-2-piperidin-1-ylthiophene; N-Methyl-1-[5-[(methylamino)methyl]thiophen-2-yl]piperidin-1-ium; (5-Piperidinothiophen-2-yl)-N-methylmethanamine
EINECS	Contact for details

Quality Control

Our n-Methyl-[(5-Piperidinothien-2-Yl)Methyl]Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.