Description

Methyl 5-Chloro-3-Hydroxythiophene-2-Carboxylate is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique thiophene core, functionalized with chloro, hydroxyl, and ester groups, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Synthesis: Serves as a crucial building block for developing advanced pesticides, herbicides, and fungicides with enhanced efficacy and selectivity.
• Material Science Precursor: Used in the synthesis of functionalized polymers, organic semiconductors, and conductive materials due to its electron-rich thiophene structure.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for complex organic transformations, including cross-coupling reactions and heterocyclic chemistry.
• Dye and Pigment Intermediate: Acts as a precursor for synthesizing specialized dyes and pigments with specific light-absorption properties.

Basic Information

Product Name	Methyl 5-Chloro-3-Hydroxythiophene-2-Carboxylate
CAS No.	953092-76-7
Molecular Formula	C7H5ClO3S
Molecular Weight	204.63 g/mol
Synonyms	5-Chloro-3-hydroxy-2-thiophenecarboxylic acid methyl ester; Methyl 5-chloro-3-hydroxy-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 5-chloro-3-hydroxy-, methyl ester; 953092-76-7; 5-Chloro-3-hydroxythiophene-2-carboxylic acid methyl ester; 3-Hydroxy-5-chlorothiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Chloro-3-Hydroxythiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.