Description

[3-(2-Fluoro-Phenyl)-Isoxazol-5-Yl]-Methanol is a high-purity fluorinated isoxazole derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique heterocyclic structure, which serves as a versatile scaffold for developing novel active compounds. This intermediate is essential for research and development teams in the pharmaceutical and agrochemical industries seeking to create new molecules with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used as a core structural component in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated isoxazole moiety.
• Chemical Biology Probe: Serves as a building block for creating molecular probes to study enzyme function and biological pathways in academic and industrial R&D settings.
• Material Science Precursor: Potential intermediate in the synthesis of specialty polymers and advanced materials requiring fluorinated heterocyclic units for specific electronic or physical properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	[3-(2-Fluoro-Phenyl)-Isoxazol-5-Yl]-Methanol
CAS No.	953046-62-3
Molecular Formula	C10H8FNO2
Molecular Weight	193.17 g/mol
Synonyms	5-(Hydroxymethyl)-3-(2-fluorophenyl)isoxazole; (3-(2-Fluorophenyl)isoxazol-5-yl)methanol; 2-Fluoro-β-(5-(hydroxymethyl)isoxazol-3-yl)benzenemethanol; [3-(2-Fluorophenyl)-1,2-oxazol-5-yl]methanol; Fluorinated Isoxazole Methanol Derivative
EINECS	Contact for details

Quality Control

Our [3-(2-Fluoro-Phenyl)-Isoxazol-5-Yl]-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.