Description

(R)-(+)-1-Phenyl-1-Propanol CAS NO 1565-74-8 is a high-purity chiral secondary alcohol, serving as a critical chiral building block and resolving agent in asymmetric synthesis. Its value lies in its ability to impart stereochemical control, enabling the production of enantiomerically pure intermediates for advanced pharmaceuticals and fine chemicals. This product is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high optical purity for developing active pharmaceutical ingredients (APIs) and other high-value compounds.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key precursor for the manufacture of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalyst and Ligand Precursor: Used in the development and synthesis of chiral ligands for transition metal catalysis.
• Chiral Resolving Agent: Employed for the separation of racemic mixtures of acids or other chiral compounds via diastereomeric salt formation.
• Agrochemical Intermediate: Utilized in the synthesis of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Flavor and Fragrance Ingredient Synthesis: Acts as a building block for creating stereospecific aroma chemicals.
• Academic and Industrial R&D: Serves as a standard and reagent in methodological development for new asymmetric transformations.

Basic Information

Product Name	(R)-(+)-1-Phenyl-1-Propanol
CAS No.	1565-74-8
Molecular Formula	C9H12O
Molecular Weight	136.19 g/mol
Synonyms	(R)-(+)-1-Phenyl-1-propanol; (R)-1-Phenylpropan-1-ol; (+)-(R)-1-Phenyl-1-propanol; (R)-α-Ethylbenzyl alcohol; (R)-1-Phenylpropyl alcohol; (R)-sec-Phenethyl alcohol; (R)-Hydroxy(ethyl)benzene; (R)-Phenyl ethyl carbinol
EINECS	Contact for details

Quality Control

Our (R)-(+)-1-Phenyl-1-Propanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for optical purity and chemical identity. Certificates of Analysis (COA) detailing specific optical rotation, enantiomeric excess (ee), chemical purity, and identity are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Specific Optical Rotation [α]	+40.0° to +44.0° (c=1 in ethanol)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.