Description

4-[3-(Methylamino)-1-(2-Thienyl)Propyl]-1-Naphthalenol Hydrochloride is a high-purity, synthetic organic compound of significant interest in advanced pharmaceutical research and development. This specialized chemical serves as a critical intermediate or reference standard in the synthesis and study of novel therapeutic agents, particularly those targeting neurological pathways. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the production of innovative active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, particularly for central nervous system (CNS) targets.
• Reference Standard: Used as a certified standard in analytical method development and validation for quality control of active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in in vitro studies to investigate receptor binding affinity, enzyme inhibition, and other pharmacological mechanisms of action.
• Process Chemistry Development: Serves as a model compound for optimizing synthetic routes, scaling up production, and improving yield and purity in pilot plants.
• Academic Research: Utilized by universities and research institutes for medicinal chemistry projects and the discovery of new bioactive molecules.

Basic Information

Item	Details
Product Name	4-[3-(Methylamino)-1-(2-Thienyl)Propyl]-1-Naphthalenol Hydrochloride
CAS No.	953028-76-7
Molecular Formula	C₁₈H₂₂ClNOS
Molecular Weight	335.89 g/mol
Synonyms	1-Naphthalenol, 4-[3-(methylamino)-1-(2-thienyl)propyl]-, hydrochloride; 4-(3-(Methylamino)-1-(thiophen-2-yl)propyl)naphthalen-1-ol hydrochloride; (R,S)-4-[3-(Methylamino)-1-(2-thienyl)propyl]-1-naphthalenol hydrochloride; N-Methyl-3-(1-hydroxy-4-naphthyl)-3-(2-thienyl)propylamine hydrochloride; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of 4-[3-(Methylamino)-1-(2-Thienyl)Propyl]-1-Naphthalenol Hydrochloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.