Description

Methyl 2-tert-Butyl-5-Nitro-1H-Indole-7-Carboxylate is a high-purity, synthetically valuable indole derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique, sterically hindered structure makes it an essential building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for innovative synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its indole scaffold.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and medicinal chemistry.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags or molecular probes to study biological processes.

Basic Information

Product Name	Methyl 2-tert-Butyl-5-Nitro-1H-Indole-7-Carboxylate
CAS No.	952665-00-8
Molecular Formula	C15H18N2O4
Molecular Weight	290.32 g/mol
Synonyms	Methyl 2-(tert-butyl)-5-nitro-1H-indole-7-carboxylate; 7-Carbomethoxy-2-tert-butyl-5-nitroindole; 2-tert-Butyl-5-nitro-1H-indole-7-carboxylic acid methyl ester; 5-Nitro-2-tert-butylindole-7-carboxylic acid methyl ester; 952665-00-8; Methyl 2-tert-butyl-5-nitroindole-7-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-tert-Butyl-5-Nitro-1H-Indole-7-Carboxylate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against established internal specifications using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.