Description

2-tert-Butyl-5-Nitro-1H-Indole-7-Carboxylic Acid is a high-purity, synthetically valuable indole derivative characterized by its nitro and carboxylic acid functional groups. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the development of novel active molecules. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating complex heterocyclic structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, amide bond formation, and other transformations to construct complex molecular architectures.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and organic electronic materials.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	2-tert-Butyl-5-Nitro-1H-Indole-7-Carboxylic Acid
CAS No.	952664-99-2
Molecular Formula	C₁₃H₁₄N₂O₄
Molecular Weight	262.26 g/mol
Synonyms	2-(tert-Butyl)-5-nitro-1H-indole-7-carboxylic acid; 7-Carboxy-2-tert-butyl-5-nitroindole; 5-Nitro-2-tert-butyl-1H-indole-7-carboxylic acid; 952664-99-2; 2-tert-Butyl-5-nitroindole-7-carboxylic acid; 2-(1,1-Dimethylethyl)-5-nitro-1H-indole-7-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-tert-Butyl-5-Nitro-1H-Indole-7-Carboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.