Description

2-tert-Butyl-5-Nitro-1H-Indole-7-Carbonitrile is a specialized indole derivative, a high-value intermediate in advanced organic synthesis. Its unique structure, featuring both nitro and nitrile functional groups on the indole core, makes it a critical building block for the development of complex molecules. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Material Science: Acts as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Chemical Synthesis: Employed in academic and industrial laboratories for methodological studies and the construction of complex, polyfunctional heterocyclic compounds.
• Dye & Pigment Intermediate: Utilized in the research and development of specialized dyes and pigments due to the chromophoric indole-nitronitrile system.

Basic Information

Product Name	2-tert-Butyl-5-Nitro-1H-Indole-7-Carbonitrile
CAS No.	952664-97-0
Molecular Formula	C₁₃H₁₃N₃O₂
Molecular Weight	243.26 g/mol
Synonyms	2-(tert-Butyl)-5-nitro-1H-indole-7-carbonitrile; 5-Nitro-2-tert-butyl-1H-indole-7-carbonitrile; 7-Cyano-2-tert-butyl-5-nitroindole; 2-tert-Butyl-5-nitroindole-7-carbonitrile; 952664-97-0; tert-Butyl 5-nitro-7-cyanoindole
EINECS	Contact for details

Quality Control

Our 2-tert-Butyl-5-Nitro-1H-Indole-7-Carbonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.