Description

2-tert-Butyl-7-Fluoro-5-Nitro-1H-Indole is a high-purity, synthetically valuable fluorinated indole derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the introduction of both fluorine and nitro functional groups. It is primarily required by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its unique fluorinated indole structure.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials.
• Academic & Contract Research: Employed in universities and CROs for methodological studies in fluorination chemistry and heterocyclic compound synthesis.
• Dye & Pigment Industry: Acts as a starting material for synthesizing specialized fluorinated colorants and imaging agents.

Basic Information

Product Name	2-tert-Butyl-7-Fluoro-5-Nitro-1H-Indole
CAS No.	952664-94-7
Molecular Formula	C₁₂H₁₃FN₂O₂
Molecular Weight	236.24 g/mol
Synonyms	2-(tert-Butyl)-7-fluoro-5-nitro-1H-indole; 7-Fluoro-5-nitro-2-tert-butyl-1H-indole; 1H-Indole, 2-(1,1-dimethylethyl)-7-fluoro-5-nitro-; 2-tert-Butyl-7-fluoro-5-nitroindole; 952664-94-7; 7-Fluoro-5-nitro-2-(tert-butyl)indole; 2-(tert-Butyl)-7-fluoro-5-nitroindole
EINECS	Contact for details

Quality Control

Our 2-tert-Butyl-7-Fluoro-5-Nitro-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.