Description

2-tert-Butyl-1-Methyl-5-Nitro-1H-Indole is a specialized nitro-substituted indole derivative, a key building block in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of complex molecules, particularly in pharmaceutical research and material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Research: Used in the development and optimization of new active ingredients for crop protection products.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a precursor or dopant in the synthesis of advanced organic electronic materials due to the indole and nitro functional groups.
• Dye and Pigment Synthesis: Functions as an intermediate in the production of specialized dyes and pigments where the nitro-indole structure imparts specific color or light-absorption properties.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including novel cross-coupling and functionalization reactions.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for metal catalysis or as a framework for organocatalysts.

Basic Information

Product Name	2-tert-Butyl-1-Methyl-5-Nitro-1H-Indole
CAS No.	952664-81-2
Molecular Formula	C₁₃H₁₆N₂O₂
Molecular Weight	232.28 g/mol
Synonyms	1H-Indole, 2-(1,1-dimethylethyl)-1-methyl-5-nitro-; 2-tert-Butyl-1-methyl-5-nitroindole; 5-Nitro-2-tert-butyl-1-methylindole; 2-(tert-Butyl)-1-methyl-5-nitro-1H-indole; 1-Methyl-2-tert-butyl-5-nitroindole; 952664-81-2; 2-tert-Butyl-1-methyl-5-nitroindole
EINECS	Contact for details

Quality Control

Our 2-tert-Butyl-1-Methyl-5-Nitro-1H-Indole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere if prolonged exposure is anticipated to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.