Description

2(1H)-Isoquinolinecarboxylic Acid, 8-Amino-5-Bromo-7-(2-Chloroacetyl)-3,4-Dihydro-, Ethyl Ester is a high-purity, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring a precise, reactive intermediate to construct complex molecular architectures. It is primarily utilized in the development of novel active pharmaceutical ingredients (APIs) and specialized agrochemicals, where its unique substitution pattern enables targeted modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel isoquinoline-based drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in developing next-generation herbicides and fungicides, leveraging its halogenated structure for enhanced bioactivity.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing complex heterocycles in medicinal and process chemistry.
• Chemical Biology Probe Development: Employed in creating labeled compounds and molecular probes for studying biological pathways and enzyme inhibition.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with specific optical or electronic properties.

Basic Information

Product Name	2(1H)-Isoquinolinecarboxylic Acid, 8-Amino-5-Bromo-7-(2-Chloroacetyl)-3,4-Dihydro-, Ethyl Ester
CAS No.	952598-11-7
Molecular Formula	C14H14BrClN2O3
Molecular Weight	373.63 g/mol
Synonyms	Ethyl 8-Amino-5-bromo-7-(2-chloroacetyl)-3,4-dihydro-2(1H)-isoquinolinecarboxylate; 8-Amino-5-bromo-7-(2-chloroacetyl)-3,4-dihydro-2(1H)-isoquinolinecarboxylic Acid Ethyl Ester; 952598-11-7; 8-Amino-5-bromo-7-(chloroacetyl)-3,4-dihydroisoquinoline-2(1H)-carboxylic acid ethyl ester; 5-Bromo-8-amino-7-(2-chloroacetyl)-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of 2(1H)-Isoquinolinecarboxylic Acid, 8-Amino-5-Bromo-7-(2-Chloroacetyl)-3,4-Dihydro-, Ethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure consistency and compliance with research-grade standards. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.