Description

2(1H)-Isoquinolinecarboxylic Acid, 8-Amino-7-(2-Chloroacetyl)-3,4-Dihydro-5-Phenyl-, Ethyl Ester is a specialized, high-purity organic intermediate of significant interest in advanced synthetic chemistry. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs) and complex heterocyclic compounds. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in innovative drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel isoquinoline-based drug candidates, particularly for central nervous system (CNS) and anti-infective applications.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its complex heterocyclic structure for biological activity.
• Fine Chemical Synthesis: Acts as a versatile building block for constructing complex molecular architectures in custom synthesis and material science research.
• Academic & R&D: Employed in university and corporate research laboratories for studying heterocyclic chemistry, reaction mechanisms, and developing new synthetic methodologies.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions in pharmaceutical manufacturing.

Basic Information

Product Name	2(1H)-Isoquinolinecarboxylic Acid, 8-Amino-7-(2-Chloroacetyl)-3,4-Dihydro-5-Phenyl-, Ethyl Ester
CAS No.	952597-97-6
Molecular Formula	C20H19ClN2O3
Molecular Weight	370.83 g/mol
Synonyms	Ethyl 8-Amino-7-(2-chloroacetyl)-3,4-dihydro-5-phenyl-2(1H)-isoquinolinecarboxylate; 8-Amino-7-(2-chloroacetyl)-3,4-dihydro-5-phenyl-2(1H)-isoquinolinecarboxylic Acid Ethyl Ester; 952597-97-6; 8-Amino-7-(chloroacetyl)-3,4-dihydro-5-phenylisoquinoline-1(2H)-carboxylic acid ethyl ester; 1,2,3,4-Tetrahydro-8-amino-7-(2-chloroacetyl)-5-phenylisoquinoline-1-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to cGMP principles for the manufacture of pharmaceutical intermediates to support our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.