Description

1-Oxo-1,2,3,4-Tetrahydroisoquinoline-7-Carbaldehyde is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core structure makes it a critical intermediate for the development of novel pharmacologically active compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new molecular entities with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Serves as a building block for developing new active ingredients in herbicides, fungicides, and insecticides.
• Fine Chemical Synthesis: Used in the preparation of specialty chemicals, dyes, and advanced materials requiring the isoquinoline scaffold.
• Academic & Contract Research: An important reagent for methodological studies and the discovery of new chemical reactions in university and CRO laboratories.
• Ligand and Catalyst Development: Utilized in the design of novel chiral ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	1-Oxo-1,2,3,4-Tetrahydroisoquinoline-7-Carbaldehyde
CAS No.	952587-40-5
Molecular Formula	C10H9NO2
Molecular Weight	175.18 g/mol
Synonyms	7-Isoquinolinecarboxaldehyde, 1,2,3,4-tetrahydro-1-oxo-; 1,2,3,4-Tetrahydro-1-oxo-7-isoquinolinecarboxaldehyde; 7-Formyl-1,2,3,4-tetrahydroisoquinolin-1-one; 7-Carbaldehyde-1,2,3,4-tetrahydroisoquinolin-1-one; 1-Oxo-1,2,3,4-tetrahydro-7-isoquinolinecarbaldehyde; THIQ-7-Carbaldehyde; 952587-40-5
EINECS	Contact for details

Quality Control

Our 1-Oxo-1,2,3,4-Tetrahydroisoquinoline-7-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 15-25°C. This compound is easily oxidized; prolonged exposure to air should be avoided. Keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.