Description

4H-Indol-4-One, 1-Acetyl-1,5,6,7-Tetrahydro-5-Methylene- is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused indole core structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Serves as a structural motif in the development of new pesticides and herbicides with novel modes of action.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex heterocyclic compounds due to its reactive methylene and carbonyl groups.
• Material Science Research: Potential application in the synthesis of organic electronic materials and specialty dyes.

Basic Information

Product Name	4H-Indol-4-One, 1-Acetyl-1,5,6,7-Tetrahydro-5-Methylene-
CAS No.	952428-39-6
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	1-Acetyl-5-methylidene-1,5,6,7-tetrahydro-4H-indol-4-one; 1-Acetyl-5-methylene-1,5,6,7-tetrahydro-4H-indol-4-one; 5-Methylene-1-acetyl-1,5,6,7-tetrahydro-4H-indol-4-one; 952428-39-6; 1-Acetyl-5-methylidene-6,7-dihydro-1H-indol-4(5H)-one
EINECS	Contact for details

Quality Control

Our 4H-Indol-4-One, 1-Acetyl-1,5,6,7-Tetrahydro-5-Methylene- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.