Description

6-(1,1-Dioxoisothiazolidin-2-Yl)-1H-Indazole is a high-purity, heterocyclic organic compound featuring a fused indazole and isothiazolidine dioxide structure. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, particularly in therapeutic areas targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Serves as a core scaffold or a functionalized building block for structure-activity relationship (SAR) studies and library synthesis.
• Biochemical Probe Development: Used in the design and synthesis of chemical probes for investigating biological targets and mechanisms of action.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce the unique indazole-isothiazolidinone moiety into complex molecules.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	6-(1,1-Dioxoisothiazolidin-2-Yl)-1H-Indazole
CAS No.	952183-42-5
Molecular Formula	C10H9N3O2S
Molecular Weight	235.26 g/mol
Synonyms	6-(1,1-Dioxo-1,2-thiazolidin-2-yl)-1H-indazole; 2-(1H-Indazol-6-yl)-1,2-thiazolidine 1,1-dioxide; 1H-Indazole, 6-(1,1-dioxido-2-isothiazolidinyl)-; 6-(1,1-Dioxo-1λ⁶,2-thiazolidin-2-yl)-1H-indazole; 6-(1,1-Dioxoisothiazolidin-2-yl)-1H-indazole; 6-(1,1-Dioxothiazolidin-2-yl)-1H-indazole
EINECS	Contact for details

Quality Control

Our production of 6-(1,1-Dioxoisothiazolidin-2-Yl)-1H-Indazole adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.