Description

N'-(1H-Indazol-5-Yl)-N,n-Dimethyliminoformamide is a high-purity advanced pharmaceutical intermediate with a defined molecular structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, especially within oncology and kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of targeted small-molecule drugs.
• Kinase Inhibitor Development: Core scaffold for research into protein kinase inhibitors due to the indazole moiety.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Assay Development: Serves as a reference standard or probe compound in high-throughput screening.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for chemical biology and drug discovery projects.

Basic Information

Product Name	N'-(1H-Indazol-5-Yl)-N,n-Dimethyliminoformamide
CAS No.	952183-04-9
Molecular Formula	C₁₁H₁₃N₅O
Molecular Weight	231.26 g/mol
Synonyms	N'-(1H-Indazol-5-yl)-N,N-dimethylformamidine; 5-[(Dimethylamino)methylideneamino]-1H-indazole; N,N-Dimethyl-N'-(1H-indazol-5-yl)formamidine; 952183-04-9; N-(1H-Indazol-5-yl)-N',N'-dimethylformamidine; N'-(1H-Indazol-5-yl)-N,N-dimethylmethanimidamide
EINECS	Contact for details

Quality Control

Our N'-(1H-Indazol-5-Yl)-N,n-Dimethyliminoformamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under inert conditions for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.