Description

1,2-Dihydro-2-Oxo-Pyridin-3-Ylboronic Acid is a specialized boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its primary value lies in its role as a versatile building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system and other therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key boron-containing partner for constructing carbon-carbon bonds to create complex biaryl and heterobiaryl structures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of enzyme inhibitors or molecular probes.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in research laboratories worldwide.

Basic Information

Product Name	1,2-Dihydro-2-Oxo-Pyridin-3-Ylboronic Acid
CAS No.	951655-49-5
Molecular Formula	C5H6BNO3
Molecular Weight	138.92 g/mol
Synonyms	3-Pyridinylboronic Acid, 1,2-Dihydro-2-oxo-; 2-Oxo-1,2-dihydropyridin-3-ylboronic Acid; 2-Hydroxypyridin-3-ylboronic Acid; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one; 2(1H)-Pyridinone, 3-borono-; 3-Boronopyridin-2(1H)-one; 2-Hydroxy-3-pyridineboronic acid
EINECS	Contact for details

Quality Control

Our 1,2-Dihydro-2-Oxo-Pyridin-3-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Custom synthesis and purification to meet specific research or cGMP guidelines are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.