Description

1H-Benzimidazol-2-Amine, 6-[(Aminooxy)Methyl]- (CAS 951327-75-6) is a specialized benzimidazole derivative featuring a reactive aminooxy functional group. This unique molecular structure makes it a valuable key intermediate and building block in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical sectors for creating compounds with targeted biological or chemical properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways or requiring oxime-based conjugation.
• Agrochemical Research: Used as a building block for developing new fungicides, herbicides, or plant growth regulators with enhanced efficacy.
• Bioconjugation & Linker Chemistry: The aminooxy group enables efficient and selective conjugation to aldehydes and ketones, making it useful for creating antibody-drug conjugates (ADCs), diagnostic probes, and polymer-functionalized materials.
• Material Science: Serves as a monomer or functionalizing agent in the production of specialty polymers, coatings, or resins with tailored chemical properties.
• Chemical Biology Tool: Employed in research for labeling biomolecules or constructing chemical probes to study biological processes.
• Academic & Contract Research: A valuable reagent for synthetic chemistry research in universities and contract research organizations (CROs).

Basic Information

Product Name	1H-Benzimidazol-2-Amine, 6-[(Aminooxy)Methyl]-
CAS No.	951327-75-6
Molecular Formula	C8H10N4O
Molecular Weight	178.19 g/mol
Synonyms	6-(Aminooxymethyl)-1H-benzimidazol-2-amine; 2-Amino-6-(aminooxymethyl)-1H-benzimidazole; 6-(Aminooxymethyl)-2-benzimidazolamine; 6-(Hydroxyamino)methyl-2-aminobenzimidazole; 951327-75-6; Benzimidazole, 2-amino-6-[(aminooxy)methyl]-; (6-(Aminooxymethyl)-1H-benzo[d]imidazol-2-yl)amine
EINECS	Contact for details

Quality Control

Our production of 1H-Benzimidazol-2-Amine, 6-[(Aminooxy)Methyl]- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure consistent high quality and reproducibility for your critical research and synthesis work. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.