Description

(R)-2-(6-Methyl-5-Nitro-1-Oxoisoquinolin-2(1H)-Yl)Propyl Acetate is a high-purity, chiral isoquinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel pharmaceutical agents and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, process chemistry, and the synthesis of complex, optically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Asymmetric Synthesis: Employed as a sophisticated building block in catalytic asymmetric reactions to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to explore novel chemical space.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for candidate drugs.
• Chemical Biology Probes: Potential use in the synthesis of labeled compounds or probes for studying biological pathways and target engagement.

Basic Information

Product Name	(R)-2-(6-Methyl-5-Nitro-1-Oxoisoquinolin-2(1H)-Yl)Propyl Acetate
CAS No.	951016-19-6
Molecular Formula	C₁₅H₁₆N₂O₅
Molecular Weight	304.30 g/mol
Synonyms	(R)-2-(6-Methyl-5-nitro-1-oxo-1,2-dihydroisoquinolin-2-yl)propyl acetate; (2R)-2-(6-Methyl-5-nitro-1-oxoisoquinolin-2-yl)propyl acetate; 951016-19-6; (R)-enantiomer of 2-(6-Methyl-5-nitro-1-oxo-1,2-dihydroisoquinolin-2-yl)propyl acetate; Propyl acetate, 2-(6-methyl-5-nitro-1-oxo-1,2-dihydroisoquinolin-2-yl)-, (2R)-
EINECS	Contact for details

Quality Control

Our production of (R)-2-(6-Methyl-5-Nitro-1-Oxoisoquinolin-2(1H)-Yl)Propyl Acetate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), enantiomeric excess (ee), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.