Description

3-Isoquinolinecarboxamide, n-Cyclopropyl-n-[[3-[4-(1-Pyrrolidinyl)-6-Quinazolinyl]Phenyl]Methyl]- is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound matters for its role as a key synthetic building block in the development of targeted small-molecule therapeutics, particularly kinase inhibitors. It is primarily needed by R&D departments and process chemists in the pharmaceutical and biotechnology industries engaged in oncology and anti-inflammatory research programs. Its complex heterocyclic structure makes it a valuable scaffold for creating novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel kinase inhibitors for oncology and immunology research.
• Drug Discovery Scaffold: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its quinazoline and isoquinoline motifs.
• Biochemical Research: Employed as a reference standard or tool compound in enzymatic assays and target validation studies.
• Process Development: Utilized in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Custom Synthesis: Acts as a starting material for the contract manufacturing of specialized, high-value chemical entities for clinical trials.

Basic Information

Product Name	3-Isoquinolinecarboxamide, n-Cyclopropyl-n-[[3-[4-(1-Pyrrolidinyl)-6-Quinazolinyl]Phenyl]Methyl]-
CAS No.	950569-12-7
Molecular Formula	C32H31N5O
Molecular Weight	501.63 g/mol
Synonyms	N-Cyclopropyl-N-({3-[4-(pyrrolidin-1-yl)quinazolin-6-yl]phenyl}methyl)isoquinoline-3-carboxamide; 950569-12-7; UNII-8U8KQ6K2QN; 8U8KQ6K2QN; CHEMBL3186666; BDBM50389345; AKOS009158932; ZINC000003869793; n-Cyclopropyl-n-[[3-[4-(1-Pyrrolidinyl)-6-Quinazolinyl]Phenyl]Methyl]-3-Isoquinolinecarboxamide
EINECS	Contact for details

Quality Control

Our 3-Isoquinolinecarboxamide derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We support development projects requiring material produced under GMP guidelines and can provide documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.