Description

3-Isoquinolinecarboxamide, n-[[3-[4-(Diethylamino)-6-Quinazolinyl]Phenyl]Methyl]-n-Methyl- is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound matters for its role as a key building block in the synthesis of targeted therapeutic agents, particularly kinase inhibitors. Pharmaceutical R&D and fine chemical synthesis companies need this material for developing novel treatments in oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel kinase inhibitor candidates targeting specific disease pathways.
• Oncology Research: Used in the development and optimization of small-molecule drugs for cancer therapy.
• Biochemical Screening: Serves as a reference standard or a core scaffold in high-throughput screening libraries for drug discovery.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies and lead optimization processes in academic and industrial labs.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring a complex, functionalized heterocyclic core.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for GMP and non-GMP production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3-Isoquinolinecarboxamide, n-[[3-[4-(Diethylamino)-6-Quinazolinyl]Phenyl]Methyl]-n-Methyl-
CAS No.	950568-48-6
Molecular Formula	C30H30N6O
Molecular Weight	490.60 g/mol
Synonyms	N-[[3-[4-(Diethylamino)-6-quinazolinyl]phenyl]methyl]-N-methyl-3-isoquinolinecarboxamide; 950568-48-6; 3-Isoquinolinecarboxamide, N-[[3-[4-(diethylamino)-6-quinazolinyl]phenyl]methyl]-N-methyl-; N-Methyl-N-({3-[4-(diethylamino)quinazolin-6-yl]phenyl}methyl)isoquinoline-3-carboxamide; Kinase Inhibitor Intermediate; Quinazoline-Isoquinoline Hybrid Compound
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We can supply material compliant with ICH guidelines for stability and impurity characterization upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The material should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.