Description

6-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-, Ethyl Ester, Hydrochloride is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. Its value lies in its complex isoquinoline core structure, which is integral to the synthesis of bioactive molecules and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex alkaloids and potential drug candidates targeting neurological and cardiovascular systems.
• Organic Synthesis Building Block: Used in multi-step synthesis for constructing complex heterocyclic frameworks due to its reactive ester and tetrahydroisoquinoline groups.
• Agrochemical Research: Serves as a starting material for developing novel pesticides and herbicides with specific biological activity.
• Chemical Reference Standard: Employed in analytical laboratories for method development, validation, and quality control of related substances.
• Academic & Institutional Research: Utilized in universities and research institutes for studying organic reaction mechanisms and exploring new synthetic pathways.
• Fine Chemical Production: Incorporated into the manufacture of specialty chemicals, dyes, and functional materials.

Basic Information

Product Name	6-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-, Ethyl Ester, Hydrochloride
CAS No.	949922-64-9
Molecular Formula	C13H16ClNO2
Molecular Weight	253.72 g/mol
Synonyms	Ethyl 1,2,3,4-Tetrahydro-6-isoquinolinecarboxylate Hydrochloride; 1,2,3,4-Tetrahydro-6-isoquinolinecarboxylic Acid Ethyl Ester Hydrochloride; 6-(Ethoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline Hydrochloride; 6-Carbethoxy-1,2,3,4-tetrahydroisoquinoline HCl; 1,2,3,4-Tetrahydroisoquinoline-6-carboxylic Acid Ethyl Ester Hydrochloride; Ethyl 1,2,3,4-Tetrahydroisoquinoline-6-carboxylate Hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-, Ethyl Ester, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications in cGMP-compliant pharmaceutical development and other high-standard industrial uses.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.