Description

1-(6-Fluoro-1H-Indol-3-Yl)Ethanone is a high-purity fluorinated indole derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the 6-fluoroindole pharmacophore into novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new bioactive molecules.
• Agrochemical Development: Intermediate in the research and synthesis of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Serves as a precursor for fluorescent tags or affinity probes used in biochemical assays and diagnostic research.
• Academic & Institutional R&D: Utilized in universities and research institutes for methodological development and novel heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis houses producing specific, high-value compounds for client projects.

Basic Information

Product Name	1-(6-Fluoro-1H-Indol-3-Yl)Ethanone
CAS No.	949035-26-1
Molecular Formula	C10H8FNO
Molecular Weight	177.18 g/mol
Synonyms	3-Acetyl-6-fluoroindole; 6-Fluoro-3-acetylindole; 6-Fluoro-1H-indol-3-yl ethanone; 1-(6-Fluoro-1H-indol-3-yl)ethan-1-one; 6-Fluoroindol-3-yl methyl ketone; Ethanone, 1-(6-fluoro-1H-indol-3-yl)-; 949035-26-1; AKOS005258155
EINECS	Contact for details

Quality Control

Our 1-(6-Fluoro-1H-Indol-3-Yl)Ethanone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.