Description

1H-Indole-3-Carboxylic Acid, 7-Chloro-5-Fluoro-4-Methyl- is a high-purity, halogenated indole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which is essential for constructing complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where precise chemical structure is paramount.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used as a precursor in the synthesis of novel herbicides and pesticides, leveraging its halogenated indole core.
• Chemical Biology Probe: Serves as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique electronic or photophysical properties.
• Contract Research & Manufacturing (CRAM): Supplied to organizations requiring custom, high-purity fluorinated and chlorinated indole derivatives for client-specific projects.

Basic Information

Product Name	1H-Indole-3-Carboxylic Acid, 7-Chloro-5-Fluoro-4-Methyl-
CAS No.	948581-68-8
Molecular Formula	C10H7ClFNO2
Molecular Weight	227.62 g/mol
Synonyms	7-Chloro-5-fluoro-4-methyl-1H-indole-3-carboxylic acid; 4-Methyl-7-chloro-5-fluoroindole-3-carboxylic acid; 7-Chloro-5-fluoro-4-methylindole-3-carboxylic acid; 948581-68-8; 1H-Indole-3-carboxylic acid, 7-chloro-5-fluoro-4-methyl-; 3-Carboxy-7-chloro-5-fluoro-4-methylindole; 7-Chloro-5-fluoro-4-methyl-1H-indole-3-carboxylate (acid form)
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Carboxylic Acid, 7-Chloro-5-Fluoro-4-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.