Description

1H-Indole-3-Carboxylic Acid,5-(Trifluoromethyl)- is a high-value trifluoromethylated indole derivative, a key building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular scaffolds with enhanced physicochemical properties. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) research.
• Agrochemical Development: Used in creating novel herbicides, fungicides, and insecticides, where the trifluoromethyl group improves bioactivity and environmental stability.
• Material Science Research: Acts as a monomer or functional additive in the development of specialty polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or labeling reagent in biochemical assays and proteomics studies.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry laboratories worldwide.

Basic Information

Product Name	1H-Indole-3-Carboxylic Acid,5-(Trifluoromethyl)-
CAS No.	948579-72-4
Molecular Formula	C10H6F3NO2
Molecular Weight	229.16 g/mol
Synonyms	5-(Trifluoromethyl)-1H-indole-3-carboxylic acid; 5-Trifluoromethylindole-3-carboxylic acid; 5-Trifluoromethyl-1H-indole-3-carboxylic acid; 3-Carboxy-5-(trifluoromethyl)indole; 5-(Trifluoromethyl)indole-3-carboxylic acid; 1H-Indole-3-carboxylic acid, 5-(trifluoromethyl)-; 948579-72-4
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Carboxylic Acid,5-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.