Description

Ethanethiol, 2-[2-(2-Aminoethoxy)Ethoxy]- is a specialized bifunctional organic compound featuring both a thiol and a primary amine group, linked by a short polyether chain. This unique structure makes it a valuable heterobifunctional linker for the synthesis of complex molecules and advanced materials, particularly in bioconjugation and polymer chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and specialty polymer industries for creating custom cross-linked networks, modifying surfaces, and developing targeted drug delivery systems.

Application

• Bioconjugation Reagent: Acts as a heterobifunctional crosslinker for coupling biomolecules (e.g., proteins, peptides) to other entities via thiol-amine chemistry.
• Polymer Modification: Used as a functional monomer or chain transfer agent to introduce thiol and amine functionalities into polymer backbones for enhanced reactivity.
• Surface Functionalization: Employed to create self-assembled monolayers (SAMs) on gold or other metal surfaces, providing a reactive amine-terminated interface for further chemical attachment.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and prodrugs requiring specific thiol-ether-amine linkages.
• Material Science: Facilitates the development of hydrogels, dendrimers, and other networked materials with tunable mechanical and chemical properties.
• Chelating Agent Synthesis: Used in the preparation of novel chelating ligands for metal ions in catalytic or diagnostic applications.

Basic Information

Product Name	Ethanethiol, 2-[2-(2-Aminoethoxy)Ethoxy]-
CAS No.	948039-59-6
Molecular Formula	C6H15NO2S
Molecular Weight	165.25 g/mol
Synonyms	2-[2-(2-Aminoethoxy)ethoxy]ethanethiol; Amino-PEG2-thiol; 2,2'-(Ethylenedioxy)di(ethanamine) thiol derivative; 11-Amino-3,6,9-trioxa-1-undecanethiol; HS-PEG2-NH2; Thiol-PEG2-amine; Amino-terminated PEG thiol; 3,6-Dioxa-8-amino-1-octanethiol
EINECS	Contact for details

Quality Control

Our production of Ethanethiol, 2-[2-(2-Aminoethoxy)Ethoxy]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and industrial use. All materials are subjected to rigorous analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.