Description

2-Nitrothiophenol is a specialized aromatic thiol derivative characterized by its nitro-substituted thiophenol structure. This compound is a valuable synthetic intermediate and ligand, prized for its unique reactivity profile that facilitates the construction of complex sulfur-containing molecules and materials. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for applications ranging from catalysis to polymer modification.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thioether or disulfide linkages.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the nitro-thiophenol moiety imparts specific biological activity.
• Ligand in Catalysis: Acts as a ligand for transition metal catalysts in cross-coupling and other organic transformations, leveraging the sulfur and nitro functional groups.
• Polymer Modification: Employed to introduce functional groups into polymer chains, altering properties like adhesion, solubility, or reactivity.
• Chemical Research & Development: A versatile reagent in organic synthesis for constructing heterocycles and complex molecular architectures.
• Material Science: Investigated for use in the development of conductive polymers, self-assembled monolayers (SAMs), and other advanced materials.

Basic Information

Product Name	2-Nitrothiophenol
CAS No.	4875-10-9
Molecular Formula	C6H5NO2S
Molecular Weight	155.17 g/mol
Synonyms	2-Nitrobenzenethiol; o-Nitrothiophenol; 2-Nitrothiophenol; 2-Nitrobenzenethiol; (2-Nitrophenyl)thiol; o-Nitrobenzenethiol; 2-Nitro-1-thiophenol; 2-Nitro-phenyl mercaptan; 2-Nitrothiophenol (stabilized)
EINECS	225-507-4

Quality Control

Our 2-Nitrothiophenol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, identity, and relevant impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its properties of being easily oxidized (store under inert atmosphere) and light-sensitive, it is recommended to handle under an inert atmosphere such as nitrogen or argon and minimize exposure to air and light during use.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.