Description

1H-Indole-4-Carboxylic Acid, 6-[[(1,1-Dimethylethoxy)Carbonyl]Amino]- is a high-purity, advanced pharmaceutical intermediate featuring a strategically protected amino group on the indole scaffold. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for constructing complex heterocyclic targets.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the biological activity of indole-based compounds.
• Peptidomimetic Synthesis: The Boc-protected amino acid derivative is utilized in the design and synthesis of peptidomimetics and constrained peptides.
• Chemical Biology Probes: Acts as a precursor for developing fluorescent or affinity-based probes to study biological pathways and protein interactions.
• Agrochemical Research: Employed in the discovery and development of new agrochemicals with potential herbicidal or insecticidal properties.

Basic Information

Product Name	1H-Indole-4-Carboxylic Acid, 6-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-
CAS No.	948015-63-2
Molecular Formula	C14H16N2O4
Molecular Weight	276.29 g/mol
Synonyms	6-((tert-Butoxycarbonyl)amino)-1H-indole-4-carboxylic acid; 6-(Boc-amino)-1H-indole-4-carboxylic acid; Boc-6-Amino-1H-indole-4-carboxylic acid; tert-Butyl (4-carboxy-1H-indol-6-yl)carbamate; 6-[(tert-Butoxycarbonyl)amino]-1H-indole-4-carboxylic acid; 6-N-Boc-amino-1H-indole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 1H-Indole-4-Carboxylic Acid, 6-[[(1,1-Dimethylethoxy)Carbonyl]Amino]- is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles via validated methods such as HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.