Description

8-Bromo-2-Methyl-1,2,3,4-Tetrahydroisoquinoline is a versatile brominated tetrahydroisoquinoline derivative, a key scaffold in modern synthetic organic chemistry. This compound matters as a crucial pharmaceutical intermediate and building block for the development of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: Serves as a core building block for the synthesis of potential drug candidates targeting neurological disorders, cardiovascular diseases, and oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable bromine and methyl substituents.
• Agrochemical Synthesis: Acts as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the preparation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Precursor: Utilized in the synthesis of advanced organic materials, such as liquid crystals or organic semiconductors.
• Academic Research: A valuable reagent for methodological studies in organic synthesis, including cross-coupling reactions and C-H functionalization.

Basic Information

Product Name	8-Bromo-2-Methyl-1,2,3,4-Tetrahydroisoquinoline
CAS No.	947499-03-8
Molecular Formula	C₁₀H₁₂BrN
Molecular Weight	226.11 g/mol
Synonyms	8-Bromo-2-methyl-1,2,3,4-tetrahydroisoquinoline; 2-Methyl-8-bromo-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-8-bromo-2-methylisoquinoline; 8-Bromo-2-methyl-THIQ; 947499-03-8
EINECS	Contact for details

Quality Control

Our 8-Bromo-2-Methyl-1,2,3,4-Tetrahydroisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.