Description

tert-Butyl 4-(1H-Indol-3-yl)piperazine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine-indole hybrid scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting serotonin and dopamine receptors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biologically Active Compound Synthesis: Building block for creating molecules with potential antipsychotic, antidepressant, or anticancer properties.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying neurological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.
• Academic Research: Employed in university and institutional labs for exploratory organic synthesis and pharmacological studies.

Basic Information

Product Name	tert-Butyl 4-(1H-Indol-3-yl)piperazine-1-carboxylate
CAS No.	947498-87-5
Molecular Formula	C17H23N3O2
Molecular Weight	301.39 g/mol
Synonyms	1-Boc-4-(1H-indol-3-yl)piperazine; 1-(tert-Butoxycarbonyl)-4-(1H-indol-3-yl)piperazine; 4-(1H-Indol-3-yl)piperazine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(3-indolyl)piperazine-1-carboxylate; 1-Boc-4-(3-indolyl)piperazine; BOC-4-(1H-Indol-3-yl)piperazine; 947498-87-5; UNII-6Q1V8S5Q4H
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(1H-Indol-3-yl)piperazine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.