Description

3-(Hydroxymethyl)-1H-Indole-5-Carboxylic Acid Methyl Ester is a versatile indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a hydroxymethyl group and a methyl ester, makes it a valuable building block for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Building block for developing new generation herbicides and plant growth regulators with indole-based structures.
• Material Science: Used in the research and development of organic semiconductors and advanced polymeric materials.
• Biochemical Probe Synthesis: Intermediate for creating labeled compounds and molecular probes used in diagnostic and life science research.
• Academic & R&D: Fundamental reagent in university and industrial laboratories for methodological development and novel compound library synthesis.

Basic Information

Product Name	3-(Hydroxymethyl)-1H-Indole-5-Carboxylic Acid Methyl Ester
CAS No.	947412-98-8
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	Methyl 3-(hydroxymethyl)-1H-indole-5-carboxylate; 5-(Methoxycarbonyl)-1H-indole-3-methanol; 1H-Indole-5-carboxylic acid, 3-(hydroxymethyl)-, methyl ester; 3-Hydroxymethylindole-5-carboxylic acid methyl ester; Methyl 3-hydroxymethylindole-5-carboxylate
EINECS	Contact for details

Quality Control

Our production of 3-(Hydroxymethyl)-1H-Indole-5-Carboxylic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and hygroscopic; prolonged exposure to light, moisture, or extreme temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.