Description

tert-Butyl (2-(6-Methoxy-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-1-Yl)Ethyl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a protected amine group. This compound is critical for the synthesis of complex bioactive molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the multi-step synthesis of potential drug candidates, particularly those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Peptidomimetic Synthesis: Acts as a protected precursor for introducing benzimidazole-derived moieties into peptide-like structures to enhance stability and bioavailability.
• API Development: Employed in the development and scale-up processes for Active Pharmaceutical Ingredients (APIs) requiring this specific heterocyclic framework.
• Bioconjugation Chemistry: The carbamate protecting group allows for selective deprotection, enabling its use in creating targeted conjugates for diagnostic or therapeutic applications.

Basic Information

Product Name	tert-Butyl (2-(6-Methoxy-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-1-Yl)Ethyl)Carbamate
CAS No.	947258-10-8
Molecular Formula	C₁₅H₂₁N₃O₄
Molecular Weight	307.35 g/mol
Synonyms	1-(2-((tert-Butoxycarbonyl)amino)ethyl)-6-methoxy-1,3-dihydro-2H-benzimidazol-2-one; tert-Butyl N-[2-(6-methoxy-2-oxo-1,3-dihydrobenzimidazol-1-yl)ethyl]carbamate; Boc-6-methoxy-2-benzimidazolinone-ethylamine; 947258-10-8; (2-(6-Methoxy-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)ethyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (2-(6-Methoxy-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-1-Yl)Ethyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) documenting full specifications are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.