Description

1-Hydroxy-1,3-Dihydrobenzo[C][1,2]Oxaborole-6-Carbonitrile is a high-value, heterocyclic organic compound featuring a unique benzoxaborole core integrated with a nitrile functional group. This specialized structure makes it a critical advanced pharmaceutical intermediate and a versatile building block for modern synthetic chemistry. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes where the boronic acid/ester moiety is essential for activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique heterocyclic structure for bioactivity.
• Organic Synthesis Building Block: Acts as a versatile reagent for constructing complex molecular architectures in medicinal and process chemistry.
• Material Science Precursor: Employed in the research and development of advanced organic electronic materials and polymers.
• Biochemical Probe Development: Utilized in creating molecular probes and sensors for biological research and diagnostic applications.
• Cross-Coupling Reactions: Functions as a specialized reactant in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.

Basic Information

Item	Detail
Product Name	1-Hydroxy-1,3-Dihydrobenzo[C][1,2]Oxaborole-6-Carbonitrile
CAS No.	947162-60-9
Molecular Formula	C8H6BNO2
Molecular Weight	158.95 g/mol
Synonyms	6-Cyano-1-hydroxy-1,3-dihydro-2,1-benzoxaborole; 1-Hydroxy-3H-2,1-benzoxaborole-6-carbonitrile; 6-CN-1-OH-Benzooxaborole; Benzoxaborole-6-carbonitrile derivative; 1,3-Dihydro-1-hydroxybenzo[c][1,2]oxaborole-6-carbonitrile; 6-Cyanobenzooxaborol-1-ol; (6-Cyano-1,3-dihydro-2,1-benzoxaborol-1-yl)oxidanyl
EINECS	Contact for details

Quality Control

Our production of 1-Hydroxy-1,3-Dihydrobenzo[C][1,2]Oxaborole-6-Carbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, the product must be stored in a cool, dry place, ideally at 2-8°C under an inert atmosphere for long-term stability. The container should be kept tightly sealed in a desiccator to minimize exposure to moisture. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.