Description

5-Bromo-3-tert-Butoxycarbonylamino-Thiophene-2-Carboxylicacidmethylester is a high-purity, specialized heterocyclic building block designed for advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the life sciences industry for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. Its unique bromine and protected amine functionalities offer versatile sites for further chemical elaboration.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those containing thiophene cores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific heterocyclic scaffolds.
• Material Science: Serves as a precursor for functionalized monomers in the creation of conductive polymers or specialty materials.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for target identification and validation studies.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical reactions.

Basic Information

Product Name	5-Bromo-3-tert-Butoxycarbonylamino-Thiophene-2-Carboxylicacidmethylester
CAS No.	946604-99-5
Molecular Formula	C11H14BrNO4S
Molecular Weight	336.20 g/mol
Synonyms	Methyl 5-bromo-3-[(tert-butoxycarbonyl)amino]thiophene-2-carboxylate; 5-Bromo-3-[(tert-butoxycarbonyl)amino]-2-thiophenecarboxylic acid methyl ester; 5-Bromo-3-(Boc-amino)thiophene-2-carboxylic acid methyl ester; Boc-5-Bromo-3-aminothiophene-2-carboxylic acid methyl ester; 946604-99-5; tert-Butyl N-(5-bromo-2-(methoxycarbonyl)thiophen-3-yl)carbamate
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-tert-Butoxycarbonylamino-Thiophene-2-Carboxylicacidmethylester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.