Description

(5Z,8Z,11Z,14Z,17Z)-n-(1,1,2,2-Tetradeuterio-2-Hydroxyethyl)Icosa-5,8,11,14,17-Pentaenamide is a deuterated analog of the endogenous cannabinoid receptor ligand, anandamide. This compound is a critical stable isotope-labeled standard used for precise quantitative analysis in mass spectrometry. It is primarily required by pharmaceutical research and analytical chemistry laboratories for method development, validation, and high-accuracy bioanalytical studies.

Application

• Internal Standard for LC-MS/MS: Serves as a quantitative reference standard in the analysis of endocannabinoids in biological matrices (plasma, serum, tissue).
• Metabolic Pathway Research: Used in tracer studies to investigate the biosynthesis, degradation, and metabolic fate of anandamide and related lipid mediators.
• Drug Discovery & Development: Employed in pharmacokinetic (PK) and pharmacodynamic (PD) studies for cannabinoid receptor-targeting therapeutics.
• Clinical Diagnostics: Enables accurate measurement of endocannabinoid system biomarkers for research into neurological, inflammatory, and metabolic disorders.
• Forensic Toxicology: Used as a high-purity reference material in the confirmation and quantification of cannabinoid-related compounds.
• Quality Control in Reference Material Production: Acts as a certified reference material (CRM) for calibrating analytical instruments and validating methods.

Basic Information

Product Name	(5Z,8Z,11Z,14Z,17Z)-n-(1,1,2,2-Tetradeuterio-2-Hydroxyethyl)Icosa-5,8,11,14,17-Pentaenamide
CAS No.	946524-41-0
Molecular Formula	C22H33D4NO2
Molecular Weight	351.55 g/mol (for C22H33D4NO2)
Synonyms	Deuterated Anandamide (d4-Anandamide); N-(2-Hydroxyethyl-1,1,2,2-d4)-5Z,8Z,11Z,14Z,17Z-eicosapentaenamide; AEA-d4; N-Arachidonoylethanolamine-d4; 5Z,8Z,11Z,14Z,17Z-Eicosapentaenoyl ethanolamine-d4; N-(2-Hydroxyethyl-1,1,2,2-d4)-5,8,11,14,17-eicosapentaenamide; Deuterium Labeled Anandamide
EINECS	Contact for details

Quality Control

Every batch of our deuterated standards is manufactured and analyzed under strict quality protocols to ensure isotopic purity and chemical integrity. Our quality system includes rigorous testing for identity, assay, and isotopic enrichment via techniques such as NMR and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing batch-specific results. We support compliance with GMP and ISO 17034 guidelines for reference material producers.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Under these conditions, the product is stable for at least 24 months from the date of receipt. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Isotopic Purity (d4)	≥ 98 atom % D
Chemical Purity (Titration/NMR)	≥ 90%
Solubility	Soluble in ethanol, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.