Description

Methyl 5-Bromo-1-Methyl-1H-Indole-3-Carboxylate is a high-purity, versatile indole derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its functionalized indole core, which provides a reactive scaffold for constructing complex heterocyclic molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for drug discovery and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole structure for biological activity.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic chemistry and catalysis.
• Chemical Library Synthesis: A valuable building block for creating diverse compound libraries used in high-throughput screening (HTS) campaigns.

Basic Information

Product Name	Methyl 5-Bromo-1-Methyl-1H-Indole-3-Carboxylate
CAS No.	946427-09-4
Molecular Formula	C11H10BrNO2
Molecular Weight	268.11 g/mol
Synonyms	5-Bromo-1-methyl-1H-indole-3-carboxylic acid methyl ester; Methyl 5-bromo-1-methylindole-3-carboxylate; 1-Methyl-5-bromoindole-3-carboxylic acid methyl ester; 946427-09-4; 5-Bromo-1-methylindole-3-carboxylic acid methyl ester; 3-Carbomethoxy-5-bromo-1-methylindole
EINECS	Contact for details

Quality Control

Every batch of Methyl 5-Bromo-1-Methyl-1H-Indole-3-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.