Description

n-(3,5-Bis(Trifluoromethyl)Phenyl)-2-Indol-3-Yl-2-Oxoethanamide is a high-value, specialized organic compound featuring a unique molecular architecture combining indole and trifluoromethylphenyl groups. This structure is critical for its role as a key synthetic intermediate and a potential pharmacophore in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for the development of novel active ingredients. The compound's properties make it essential for creating molecules with enhanced biological activity and specific physicochemical characteristics.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl groups can improve metabolic stability and bioavailability.
• Chemical Biology Probe: Acts as a scaffold or inhibitor in biochemical assays to study protein-protein interactions and enzyme functions.
• Material Science Precursor: Potential use in synthesizing organic electronic materials or advanced polymers due to its conjugated system and fluorine content.
• Custom Synthesis & Contract Manufacturing: A key starting material for fine chemical manufacturers offering bespoke synthesis services to R&D organizations.

Basic Information

Product Name	n-(3,5-Bis(Trifluoromethyl)Phenyl)-2-Indol-3-Yl-2-Oxoethanamide
CAS No.	946386-99-8
Molecular Formula	C18H10F6N2O2
Molecular Weight	400.28 g/mol
Synonyms	2-(1H-Indol-3-yl)-2-oxo-N-[3,5-bis(trifluoromethyl)phenyl]acetamide; N-(3,5-Bis(trifluoromethyl)phenyl)-2-(1H-indol-3-yl)-2-oxoacetamide; 2-Indol-3-yl-2-oxo-N-[3,5-bis(trifluoromethyl)phenyl]acetamide; 946386-99-8; 2-(1H-Indol-3-yl)-N-[3,5-bis(trifluoromethyl)phenyl]-2-oxoacetamide; α-Oxo-N-[3,5-bis(trifluoromethyl)phenyl]-1H-indole-3-acetamide
EINECS	Contact for details

Quality Control

Our n-(3,5-Bis(Trifluoromethyl)Phenyl)-2-Indol-3-Yl-2-Oxoethanamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications. Our commitment is to deliver material of consistent high purity and reliable performance for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.