Description

5-(((4-(4-Fluoro-3-Methylphenyl)(2,5-Thiazolyl))Amino)Methylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione is a high-value, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to develop next-generation drug candidates, leveraging its unique scaffold for creating molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in multi-step synthetic routes to construct complex molecules, particularly those containing fused thiazole and dioxane rings.
• Biochemical Research: Potential use in developing enzyme inhibitors or receptor modulators due to its specific pharmacophore features.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals for advanced material science and agrochemical research.

Basic Information

Product Name	5-(((4-(4-Fluoro-3-Methylphenyl)(2,5-Thiazolyl))Amino)Methylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione
CAS No.	946386-70-5
Molecular Formula	C18H17FN2O4S
Molecular Weight	376.40 g/mol
Synonyms	5-[(4-(4-Fluoro-3-methylphenyl)-1,3-thiazol-2-ylamino)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione; 2,2-Dimethyl-5-[[[4-(4-fluoro-3-methylphenyl)-2-thiazolyl]amino]methylene]-1,3-dioxane-4,6-dione; 946386-70-5; (5Z)-5-({[4-(4-Fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}methylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione; 5-({[4-(4-Fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione
EINECS	Contact for details

Quality Control

Our 5-(((4-(4-Fluoro-3-Methylphenyl)(2,5-Thiazolyl))Amino)Methylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles by HPLC, NMR, and MS is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.