Description

n-(2,3-Dimethyl-5-Oxo-1-Phenyl(3-Pyrazolin-4-Yl))((4-(Trifluoromethoxy)Phenyl)Amino)Formamide CAS NO 946386-37-4 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure incorporating a pyrazolinone core and a trifluoromethoxy phenylamino group. This compound is of significant commercial importance for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily needed by research institutions, custom synthesis laboratories, and pharmaceutical manufacturers engaged in the development of new chemical entities for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammatory diseases, or as kinase inhibitors.
• Agrochemical Research: Used in the research and development of new generation pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Material Science: Potential building block for specialty polymers or organic electronic materials due to its conjugated system and functional groups.
• Academic & Contract Research: Employed in academic laboratories and CROs (Contract Research Organizations) for methodological studies in heterocyclic chemistry and as a reference standard.
• Custom Synthesis: Supplied to companies requiring bespoke chemical synthesis for proprietary research and development projects.

Basic Information

Item	Details
Product Name	n-(2,3-Dimethyl-5-Oxo-1-Phenyl(3-Pyrazolin-4-Yl))((4-(Trifluoromethoxy)Phenyl)Amino)Formamide
CAS No.	946386-37-4
Molecular Formula	C19H17F3N4O3
Molecular Weight	406.36 g/mol
Synonyms	4-[[(4-Trifluoromethoxyphenyl)amino]carbonyl]amino]-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one; N-((4-(Trifluoromethoxy)phenyl)carbamoyl)-2,3-dimethyl-5-oxo-1-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide; 946386-37-4; 1-Phenyl-2,3-dimethyl-4-[[[[4-(trifluoromethoxy)phenyl]amino]carbonyl]amino]-5-pyrazolone; Formamide, N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)-N-[[4-(trifluoromethoxy)phenyl]amino]-
EINECS	Contact for details

Quality Control

Our n-(2,3-Dimethyl-5-Oxo-1-Phenyl(3-Pyrazolin-4-Yl))((4-(Trifluoromethoxy)Phenyl)Amino)Formamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing purity (typically >97% by HPLC), residual solvents, and other critical parameters are provided with every shipment to ensure full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed when not in use to prevent any potential contamination or moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.