Description

[(Triethylsilyl)Oxy]Methyl]-Pyrrolidine CAS NO 946074-05-1 is a specialized organosilicon-protected pyrrolidine derivative, serving as a crucial building block in advanced organic synthesis. Its primary value lies in its role as a protected amine synthon, enabling complex multi-step reactions with high selectivity and yield. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those containing pyrrolidine or piperidine scaffolds.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in stereoselective reactions to create enantiomerically pure compounds.
• Peptidomimetics & PROTACs: Integral for constructing advanced therapeutic modalities where the protected amine functionality is required for subsequent coupling or functionalization.
• Agrochemical Synthesis: Intermediate in the production of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a precursor for functionalized polymers or surface-modifying agents.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic and medicinal chemistry research.

Basic Information

Product Name	[(Triethylsilyl)Oxy]Methyl]-Pyrrolidine
CAS No.	946074-05-1
Molecular Formula	C12H27NOSi
Molecular Weight	229.44 g/mol
Synonyms	1-[[(Triethylsilyl)oxy]methyl]pyrrolidine; N-[[(Triethylsilyl)oxy]methyl]pyrrolidine; Pyrrolidine, 1-[[(triethylsilyl)oxy]methyl]-; (Triethylsilyloxymethyl)pyrrolidine; TES-protected aminomethylpyrrolidine; 1-(Triethylsilyloxymethyl)pyrrolidine; N-(Triethylsilyloxymethyl)pyrrolidine; Aminomethylpyrrolidine triethylsilyl ether
EINECS	Contact for details

Quality Control

Our [(Triethylsilyl)Oxy]Methyl]-Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.